Optical micromanipulation—including techniques that use light to trap and manipulate microscopic objects—was revolutionized by Arthur Ashkin’s invention of the optical tweezer in the 1980s. Optical tweezers rely on gradient and scattering forces from a tightly focused laser beam to control micro‑objects; while highly effective in controlled settings, they face limitations when handling targets of varying size, shape, or refractive index, and their high‑intensity beams can damage sensitive biological samples (e.g., cells).

In the latest issue of Science Advances, a groundbreaking research achievement has captured widespread attention in the scientific community.

Scientists continually explore precise manipulation of microscopic objects.

In an era of rapid technological advancement, laboratory innovation continues to accelerate.