Areas of Interest
Areas of Interest
Cell Line Development
We culture and isolate monoclonal cells, then perform functional validation and expression profiling to screen for stable, high-expressing cell lines on chip through OptoBot® 1000 or its series products. Our integrated workflow uses precision single-cell manipulation to screen for high-yield cell lines in as little as five days.
Cell Line Development

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Cell Line Development Kit

With the Cell Line Development kit for the OptoBot® platform,you can select productive, high-quality clones, significantly boosts screening efficiency, expedites timelines (reducing the development timeline by up to 50%) and reduces costs compared with traditional methods.

Basic Universal Kit

Provides an optimal experimental environment for your workflow.

OptoBot ®1000 Universal Kit

Optimal Kit Components

Early identify top clones with excellent quality attributes, manufacturability, and stability to reducing costs within whole bioprocess and yielding highly successful.

1. Chip Type

Chip type needed for cell line development.

OptoTrap Chip® 1750

~1,750 NanoPen chambers per chip

2. Reagents

Assess productivity by assaying monoclonal or bispecific antibodies using reagents that bind to the Fc, Kappa, and/or Lambda domain of the antibody.

Human Fc 
  • Human Fc Reagent
  • CLD Kit, Human Fc
  • CLD Kit, Human Fc + Kappa
  • CLD with Population Dynamics Kit, Human Fc
  • CLD with Population Dynamics Kit, 2-Chip, Human Fc
 Human Kappa 
  • Human Kappa Reagent
  • CLD Kit, Human Kappa
  • CLD Kit, Human Fc + Kappa
Human Lambda 
  • Human Lambda Reagent

How to Use Your Kit

1. Compatible Cell Types

Validated cell types to ensure experimental stability and reliability

CHO Cells

2. Target Molecules Measured

Traditional mAbs
Bispecific mAbs
Other biologics

3. Assay Types

Assay Type Functional Description
CLD Traditional antibody therapeutic cell line development with CHO cells.
Quality Assays Screen clones for quality attributes, such as insoluble aggregate formation and percent heterodimer for bispecific mAbs.
Stability Assessment Characterize on hundreds of subclones for your early selected clones to predict titer Stability within weeks, and correctly rank clones based on stability.