Areas of Interest
Areas of Interest
Antibody Discovery
Our process isolates single B cells and validates the function of their secreted antibodies to screen for high-affinity and high-specificity candidates. We then perform sequencing and bioinformatics analysis to create a one-to-one map between antibody sequence and function, enabling the precise identification of desired antibody sequences. Each microwell in our OptoBot® 1000 or its series products is 100,000 times smaller than a well in a standard 384-well plate. The OptoBot® 1000 or its series products supports long-term cell culture through automated medium exchange, shortening the antibody development cycle by up to two months.
Antibody Discovery

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Antibody Discovery Kits

The Antibody Discovery kit for the OptoBot® platform lets you screen plasma cells or memory B cells and find valuable monoclonal antibodies within a week. Choose from two types of OptoTrap® chips to give you the screening throughput you need for simple or difficult targets. Simplify the recovery of antigen-specific antibody sequences for downstream analysis and development using our OptoBot® B Discovery cDNA Synthesis Kit and BCR Kit .With the OptoBot® Antibody Discovery kits, you'll expedite your research and achieve more specific and effective antibody discoveries in the process.

Basic Universal Kit

Provide an optimal experimental environment for your workflow.

OptoBot ®1000 Universal Kit

Optimal Kit Components

Choose and combine antibody discovery products to customize your ideal workflow.

1. Species Sample Prep Kit

Species and cell types supported for screening.

Human
  • Memory B cells
  • Plasma cells
  • PBMC Thawing Kit
Rabbit
  • Memory B cells
  • PBMC Thawing Kit
Mouse
  • Memory B cells
  • Plasma cells
  • PBMC Thawing Kit
Alpaca
  • Memory B cells
  • PBMC Thawing Kit
Other Species

Leverage the power and flexibility of single B cell screening to develop your own reagents and workflows for other species such as cow, chicken, sheep, and goat.

2. Chip Type

Choose a Chip type for your application based on cell type and assay needs.

OptoTrap Chip® 14K Chip

~14,000 NanoPen chambers per chip​

OptoTrap Chip® 24K Chip

~24,000 NanoPen chambers per chip​

3. Assay Preparation

Beads to assess B cell Ig subtype, antigen specificity, and/or antibody function.

Assay Beads (Human)
Assay Beads (Mouse)
Assay Beads (Rabbit)
Assay Beads (Alpaca)

4. BCR Recovery Kit

Choose a BCR recovery method to recover and amplify discovered hits of interest.

Unload Type(Applicable Species) Available Kits
Cell (Human, Mouse, Rabbit, Alpaca) B Discovery cDNA Synthesis Kit
BCR Sequencing (Human, Mouse, Rabbit, Alpaca) BCR Kit
Extended BCR Bead Unload Kit (Optional)

5. Sequencing Library Prep Kit

Used for library preparation for downstream BCR sequencing.

Species Available Kits
Mouse B Discovery NGS Prep Kit, Mouse
Human B Discovery NGS Prep Kit, Human
Rabbit B Discovery NGS Prep Kit, Rabbit
Alpaca B Discovery NGS Prep Kit, Camelid
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